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Lack of communication is a big demotivator for me. I value an open and honest conversation, and it frustrates me when someone is not able to express what they feel or think. Dishonesty is another key factor; if you can't be honest with me, then there is no solid foundation on which to build something meaningful.
I like to listen and I want to be with someone who is a good listener and has the ability to put themselves in my shoes. Lack of emotional support and indifference are a red flag for me.